False positive tests in musculoskeletal medicine

How to detect false positive resisted tests?

False Positive Functional Tests Against Resistance in Musculoskeletal Examination

Functional tests against resistance are widely used in musculoskeletal (MSK) assessments to identify pain-generating structures—especially tendons, muscles, and joint-related tissues. However, these tests are not without limitations. False positives, where a test provokes symptoms unrelated to the target structure, are a common clinical challenge and can lead to misdiagnosis or unnecessary interventions.


Common Causes of False Positives

  1. Poor Patient Positioning or Technique
    • If the patient is not properly stabilized, other muscles may compensate or overload, creating discomfort not due to the intended structure.

  2. Referred Pain
    • Cervical spine or neural tissue irritation can cause pain in distal areas (e.g., arm or shoulder) during resistance tests, even when the local tissues are healthy.
    • A resisted wrist extension test might provoke forearm pain in a patient with cervical radiculopathy, mimicking lateral epicondylitis.

  3. Over-Sensitivity or Central Sensitization
    • Patients with chronic pain or heightened central sensitivity may experience pain during minimal resistance due to altered pain processing, rather than local tissue damage.

  4. Co-contraction or Anticipatory Guarding
    • In patients fearful of movement or pain, protective muscle co-contraction may lead to a painful response that is not reflective of tissue pathology.

  5. Fatigue or Overuse
    • In athletic or post-rehabilitation patients, mild discomfort during resistance testing might simply reflect recent overuse or fatigue, rather than injury.

Clinical Implications

  • Context Matters: A single positive resistance test should not be used in isolation. Always interpret it in the context of patient history, symptom pattern, and other clinical findings.
  • Compare Sides: Testing the unaffected side helps distinguish between expected effort-related discomfort and abnormal pain.
  • Use Complementary Tests: Combine resistance testing with passive range-of-motion, palpation, and neurodynamic assessments to clarify the source of symptoms.

Conclusion

False positives in resistance-based functional tests are a common but manageable issue in MSK examination. By recognizing their causes and interpreting them in clinical context, practitioners can avoid diagnostic errors and tailor more accurate, patient-centered treatment strategies.

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